Shock compression-based equation of state for perfluorohexane
Abstract
Perfluorohexane is a biocompatible material that serves as a liquid core for acoustically-responsive agents in biomedical applications. Despite its relatively widespread usage, there is a lack of experimental data determining its thermodynamic properties. This challenges numerical simulations to predict the acoustic response of agents developed using this material. In this study, we employ the well-established method of shock compression of materials at relatively high pressures (100--400 MPa) to estimate a kinematic equation of state for perfluorohexane. We use multi-objective optimization to obtain the Noble-Abel Stiffened-Gas equation of state, which is suitable for hydrodynamic numerical simulations. We then apply the extrapolated equation of state to simulate shock-wave propagation within a perfluorohexane droplet showing excellent agreement with equivalent experiments. This validates the equation of state and promotes the use of numerical simulations as a valuable tool for understanding the complex acoustic interactions involved in these biomedical agents, ultimately facilitating their translation for clinical purposes.
Keywords
Cite
@article{arxiv.2503.21306,
title = {Shock compression-based equation of state for perfluorohexane},
author = {Anunay Prasanna and Guillaume T. Bokman and Samuele Fiorini and Armand Sieber and Bratislav Lukić and Daniel Foster and Outi Supponen},
journal= {arXiv preprint arXiv:2503.21306},
year = {2026}
}