Shear unzipping of double stranded DNA
Soft Condensed Matter
2015-05-28 v3 Statistical Mechanics
Biological Physics
Abstract
We propose a simple nonlinear scaler displacement model to calculate the distribution of effect created by a shear stress on a double stranded DNA (dsDNA) molecule and the value of shear force which is required to separate the two strands of a molecule. It is shown that as long as the force pulls entire strand in the direction of its application the value of depends linearly on the length; the deviation from linear behaviour takes place when part of a strand moves in opposite direction under the influence of force acting on the other strand. The calculated values of as a function of length of dsDNA molecules are in very good agreement with the experimental values of Hatch et al (Phys. Rev. E , 011920 (2008)).
Keywords
Cite
@article{arxiv.1104.5126,
title = {Shear unzipping of double stranded DNA},
author = {Shikha Prakash and Yashwant Singh},
journal= {arXiv preprint arXiv:1104.5126},
year = {2015}
}