English

Shear unzipping of double stranded DNA

Soft Condensed Matter 2015-05-28 v3 Statistical Mechanics Biological Physics

Abstract

We propose a simple nonlinear scaler displacement model to calculate the distribution of effect created by a shear stress on a double stranded DNA (dsDNA) molecule and the value of shear force FcF_c which is required to separate the two strands of a molecule. It is shown that as long as the force pulls entire strand in the direction of its application the value of FcF_c depends linearly on the length; the deviation from linear behaviour takes place when part of a strand moves in opposite direction under the influence of force acting on the other strand. The calculated values of FcF_c as a function of length of dsDNA molecules are in very good agreement with the experimental values of Hatch et al (Phys. Rev. E 78\bf 78, 011920 (2008)).

Keywords

Cite

@article{arxiv.1104.5126,
  title  = {Shear unzipping of double stranded DNA},
  author = {Shikha Prakash and Yashwant Singh},
  journal= {arXiv preprint arXiv:1104.5126},
  year   = {2015}
}