Separating many words by counting occurrences of factors

For a given language $L$, we study the languages $X$ such that for all distinct words $u, v \in L$, there exists a word $x \in X$ that appears a different number of times as a factor in $u$ and in $v$. In particular, we are interested in the following question: For which languages $L$ does there exist a finite language $X$ satisfying the above condition? We answer this question for all regular languages and for all sets of factors of infinite words.