The increasing popularity of applications like the Metaverse has led to the exploration of new, more effective ways of communication. Semantic communication, which focuses on the meaning behind transmitted information, represents a departure from traditional communication paradigms. As mobile devices become increasingly prevalent, it is important to explore the potential of edge computing to aid the semantic encoding/decoding process, which requires significant computing power and storage capabilities. However, establishing knowledge bases (KBs) for domain-oriented communication can be time-consuming. To address this challenge, this paper proposes a semantic caching model in edge computing system that caches domain-specialized general models and user-specific individual models. This approach has the potential to reduce the time and resources required to establish individual KBs while accurately capturing the semantics behind users' messages, ultimately leading to more efficient and accessible semantic communication.