Selecting optimal minimum spanning trees that share a topological correspondence with phylogenetic trees
Abstract
Choi et. al (2011) introduced a minimum spanning tree (MST)-based method called CLGrouping, for constructing tree-structured probabilistic graphical models, a statistical framework that is commonly used for inferring phylogenetic trees. While CLGrouping works correctly if there is a unique MST, we observe an indeterminacy in the method in the case that there are multiple MSTs. In this work we remove this indeterminacy by introducing so-called vertex-ranked MSTs. We note that the effectiveness of CLGrouping is inversely related to the number of leaves in the MST. This motivates the problem of finding a vertex-ranked MST with the minimum number of leaves (MLVRMST). We provide a polynomial time algorithm for the MLVRMST problem, and prove its correctness for graphs whose edges are weighted with tree-additive distances.
Keywords
Cite
@article{arxiv.1701.02844,
title = {Selecting optimal minimum spanning trees that share a topological correspondence with phylogenetic trees},
author = {Prabhav Kalaghatgi and Thomas Lengauer},
journal= {arXiv preprint arXiv:1701.02844},
year = {2017}
}
Comments
16 pages, 5 figures