Magnetoferritin, a synthetic derivate of iron storage protein - ferritin, has been synthesized with different iron oxide loading values. Small-angle neutron scattering experiments were applied to study the structure of magnetoferritin solutions using contrast variation method by varying the light to heavy water ratio of the solvent. Higher iron loading leads to increasing of the neutron scattering length density of magnetoferritin and also to the increase of the polydispersity of complexes. The formation of the magnetic core and the variation of the protein shell structure upon iron loading are concluded.
@article{arxiv.1701.09174,
title = {SANS contrast variation study of magnetoferritin structure at various iron loading},
author = {Lucia Melnikova and Viktor I. Petrenko and Mikhail V. Avdeev and Oleksandr I. Ivankov and Leonid A. Bulavin and Vasil M. Garamus and László Almásy and Zuzana Mitroova and Peter Kopcansky},
journal= {arXiv preprint arXiv:1701.09174},
year = {2017}
}