Roadmap for Condensates in Cell Biology
Abstract
Biomolecular condensates govern essential cellular processes yet elude description by traditional equilibrium models. This roadmap, distilled from structured discussions at a workshop and reflecting the consensus of its participants, clarifies key concepts for researchers, funding bodies, and journals. After unifying terminology that often separates disciplines, we outline the core physics of condensate formation, review their biological roles, and identify outstanding challenges in nonequilibrium theory, multiscale simulation, and quantitative in-cell measurements. We close with a forward-looking outlook to guide coordinated efforts toward predictive, experimentally anchored understanding and control of biomolecular condensates.
Cite
@article{arxiv.2601.03677,
title = {Roadmap for Condensates in Cell Biology},
author = {Dilimulati Aierken and Sebastian Aland and Stefano Bo and Steven Boeynaems and Danfeng Cai and Serena Carra and Lindsay B. Case and Hue Sun Chan and Jorge R. Espinosa and Trevor K. GrandPre and Alexander Y. Grosberg and Ivar S. Haugerud and William M. Jacobs and Jerelle A. Joseph and Frank Jülicher and Kurt Kremer and Guido Kusters and Liedewij Laan and Keren Lasker and Katrin S. Laxhuber and Hyun O. Lee and Kathy F. Liu and Dimple Notani and Yicheng Qiang and Paul Robustelli and Leonor Saiz and Omar A. Saleh and Helmut Schiessel and Jeremy Schmit and Meng Shen and Krishna Shrinivas and Antonia Statt and Andres R. Tejedor and Tatjana Trcek and Christoph A. Weber and Stephanie C. Weber and Ned S. Wingreen and Huaiying Zhang and Yaojun Zhang and Huan Xiang Zhou and David Zwicker},
journal= {arXiv preprint arXiv:2601.03677},
year = {2026}
}
Comments
14 pages, 5 figures