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Reply to Chen et al.: Parametric methods for cluster inference perform worse for two-sided t-tests

Applications 2019-01-03 v1

Abstract

One-sided t-tests are commonly used in the neuroimaging field, but two-sided tests should be the default unless a researcher has a strong reason for using a one-sided test. Here we extend our previous work on cluster false positive rates, which used one-sided tests, to two-sided tests. Briefly, we found that parametric methods perform worse for two-sided t-tests, and that non-parametric methods perform equally well for one-sided and two-sided tests.

Cite

@article{arxiv.1810.02669,
  title  = {Reply to Chen et al.: Parametric methods for cluster inference perform worse for two-sided t-tests},
  author = {Anders Eklund and Hans Knutsson and Thomas E. Nichols},
  journal= {arXiv preprint arXiv:1810.02669},
  year   = {2019}
}
R2 v1 2026-06-23T04:29:39.025Z