English

Rare Event Sampling using Smooth Basin Classification

Chemical Physics 2024-05-27 v3 Statistical Mechanics

Abstract

The efficiency of atomic simulations of materials and molecules can rapidly deteriorate when large free energy barriers exist between local minima. We propose smooth basin classification, a universal method to define reaction coordinates based on the internal feature representation of a graph neural network. We achieve high data efficiency by exploiting their built-in symmetry and adopting a transfer learning strategy. We benchmark our approach on challenging chemical and physical transformations, and show that it matches and even outperforms reaction coordinates defined based on human intuition.

Keywords

Cite

@article{arxiv.2404.03777,
  title  = {Rare Event Sampling using Smooth Basin Classification},
  author = {Sander Vandenhaute and Tom Braeckevelt and Pieter Dobbelaere and Massimo Bocus and Veronique Van Speybroeck},
  journal= {arXiv preprint arXiv:2404.03777},
  year   = {2024}
}
R2 v1 2026-06-28T15:44:38.630Z