Reducing errors is critical to the application of modern quantum computers. In the current Letter, we investigate the quantum error mitigation considering parametric circuits accessible by classical computations in some range of their parameters. We present a method of global randomized error cancellations (GREC) mitigating quantum errors by summing a linear combination of additionally randomized quantum circuits with weights determined by comparison with the referent classically computable data. We illustrate the performance of this method on the example of the n=4 spins anti-ferromagnetic Ising model in the transverse field.