Quadruplex detection in human cells
Biomolecules
2019-10-17 v1 Subcellular Processes
Abstract
DNA and RNA quadruplexes are extensively studied for the key roles they are suspected to play in the cellular regulation networks at both genomic and transcriptomic levels. The reliable detection of quadruplexes in cells was and remains a challenging task. Here, we describe the various strategies that have been implemented over the past years to visualize functionally relevant DNA and RNA quadruplexes in human cells, from immunodetection studies to the design and use of quadruplex-specific turn-on fluorescent probes.
Keywords
Cite
@article{arxiv.1910.07023,
title = {Quadruplex detection in human cells},
author = {David Monchaud},
journal= {arXiv preprint arXiv:1910.07023},
year = {2019}
}
Comments
Review, 28 pages, 10 figures, 135 references