Proton Resonance Shift Thermometry: A review of modern clinical practices
Abstract
Magnetic Resonance Imaging (MRI) has become a popular modality in guiding minimally invasive thermal therapies, due to its advanced, non-ionizing, imaging capabilities and its ability to record changes in temperature. A variety of MR thermometry techniques have been developed over the years, and Proton Resonance Frequency (PRF) Shift Thermometry is the current clinical gold standard to treat a variety of cancers. It is used extensively to guide hyperthermic thermal ablation techniques such as high-intensity focused ultrasound (HIFU) and laser-induced thermal therapy (LITT). Essential attributes of PRF Shift Thermometry include excellent linearity with temperature, good sensitivity, and independence from tissue type. This non-invasive temperature mapping method gives accurate quantitative measures of the temperature evolution inside biological tissues. In this review, the current status and new developments in the fields of MR-guided HIFU and LITT are presented with an emphasis on breast, prostate, bone, uterine and brain treatments.
Keywords
Cite
@article{arxiv.2403.01219,
title = {Proton Resonance Shift Thermometry: A review of modern clinical practices},
author = {J. Blackwell and M. J. Krasny and A. O'Brien and K. Ashkan and J. Galligan and M. Destrade and N. Colgan},
journal= {arXiv preprint arXiv:2403.01219},
year = {2024}
}