English

Protein Secondary Structure Prediction Using Transformers

Artificial Intelligence 2025-12-10 v1

Abstract

Predicting protein secondary structures such as alpha helices, beta sheets, and coils from amino acid sequences is essential for understanding protein function. This work presents a transformer-based model that applies attention mechanisms to protein sequence data to predict structural motifs. A sliding-window data augmentation technique is used on the CB513 dataset to expand the training samples. The transformer shows strong ability to generalize across variable-length sequences while effectively capturing both local and long-range residue interactions.

Keywords

Cite

@article{arxiv.2512.08613,
  title  = {Protein Secondary Structure Prediction Using Transformers},
  author = {Manzi Kevin Maxime},
  journal= {arXiv preprint arXiv:2512.08613},
  year   = {2025}
}
R2 v1 2026-07-01T08:17:00.957Z