English

Properties of the Michaelis-Menten Mechanism in Phase Space

Dynamical Systems 2010-03-23 v2 Classical Analysis and ODEs

Abstract

We study the two-dimensional reduction of the Michaelis-Menten reaction of enzyme kinetics. First, we prove the existence and uniqueness of a slow manifold between the horizontal and vertical isoclines. Second, we determine the concavity of all solutions in the first quadrant. Third, we establish the asymptotic behaviour of all solutions near the origin, which generally is not given by a Taylor series. Finally, we determine the asymptotic behaviour of the slow manifold at infinity.

Keywords

Cite

@article{arxiv.math/0611119,
  title  = {Properties of the Michaelis-Menten Mechanism in Phase Space},
  author = {Matt S. Calder and David Siegel},
  journal= {arXiv preprint arXiv:math/0611119},
  year   = {2010}
}

Comments

29 pages, 8 figures, corrected a few typos and incorporated reviewer suggestions