Persistence of unknottedness of clean Lagrangian intersections

Let $Q_0$ and $Q_1$ be two Lagrangian spheres in a $6$-dimensional symplectic manifold. Assume that $Q_0$ and $Q_1$ intersect cleanly along a circle that is unknotted in both $Q_0$ and $Q_1$. We prove that there is no nearby Hamiltonian isotopy of $Q_0$ and $Q_1$ to a pair of Lagrangian spheres meeting cleanly along a circle that is knotted in either component, answering a question of Smith. The proof is based on a classification of the spherical summands in the prime decomposition of an exact Lagrangian in the Stein neighborhood of the union $Q_0\cup Q_1$ and the deep result that lens space rational Dehn surgeries characterize the unknot.