Peptide size dependent active transport in the proteasome
Biomolecules
2007-05-23 v2 Soft Condensed Matter
Abstract
We investigate the transport of proteins inside the proteasome and propose an active transport mechanism based on a spatially asymmetric interaction potential of peptide chains. The transport is driven by fluctuations which are always present in such systems. We compute the peptide-size dependent transport rate which is essential for the functioning of the proteasome. In agreement with recent experiments, varying temperature changes the transport mechanism qualitatively.
Keywords
Cite
@article{arxiv.q-bio/0311036,
title = {Peptide size dependent active transport in the proteasome},
author = {Alexei Zaikin and Thorsten Poeschel},
journal= {arXiv preprint arXiv:q-bio/0311036},
year = {2007}
}
Comments
4 pages, 4 figures