English

Pattern formation inside bacteria: fluctuations due to low copy number of proteins

Statistical Mechanics 2009-11-10 v1 Biological Physics Subcellular Processes

Abstract

We examine fluctuation effects due to the low copy number of proteins involved in pattern-forming dynamics within a bacterium. We focus on a stochastic model of the oscillating MinCDE protein system regulating accurate cell division in E. coli. We find that, for some parameter regions, the protein concentrations are low enough that fluctuations are essential for the generation of patterns. We also examine the role of fluctuations in constraining protein concentration levels.

Keywords

Cite

@article{arxiv.cond-mat/0302409,
  title  = {Pattern formation inside bacteria: fluctuations due to low copy number of proteins},
  author = {Martin Howard and Andrew D. Rutenberg},
  journal= {arXiv preprint arXiv:cond-mat/0302409},
  year   = {2009}
}

Comments

4 pages, 3 figures, accepted for publication in Phys. Rev. Lett