On the optimality of the standard genetic code: the role of stop codons
Populations and Evolution
2007-12-28 v1
Abstract
The genetic code markup is the assignment of stop codons. The standard genetic code markup ensures the maximum possible stability of genetic information with respect to two fault classes: frameshift and nonsense mutations. There are only 528 (about 1,3% of total number) optimal markups in the set of markups having 3 stop codons. Among the sets of markups with 1,2,...,8 stop codons, the standard case having 3 stop codons has maximum absolute number of optimal markups.
Cite
@article{arxiv.0712.4219,
title = {On the optimality of the standard genetic code: the role of stop codons},
author = {Sergey Naumenko and Andrew Podlazov and Mikhail Burtsev and George Malinetsky},
journal= {arXiv preprint arXiv:0712.4219},
year = {2007}
}
Comments
16 pages, 5 figures, 2 tables