English

On the incorrect use of Carlisle's method for dichotomous variables

Applications 2022-09-02 v1

Abstract

In 2017, J. B. Carlisle has proposed a method for fraud detection in randomized controlled trials based on a comparison of reported baseline data between treatment groups. While Carlisle has only used the method for continuous variables, some authors have recently employed a naive adaption of the method for dichotomous variables. We explain why such adaptation leads to p-values that are wrong by orders of magnitude and we make a simple concrete proposal for correction of the method.

Keywords

Cite

@article{arxiv.2209.00131,
  title  = {On the incorrect use of Carlisle's method for dichotomous variables},
  author = {Daniel V. Tausk},
  journal= {arXiv preprint arXiv:2209.00131},
  year   = {2022}
}

Comments

20 pages, 8 figures