On the generalized Fermat equation of signature $(5,p,3)$

In this article we study solutions to the generalized Fermat equation $x^q+y^p+z^r=0$ using hypergeometric motives within the framework of the modular method. In doing so, we give an explicit description of the ramification behavior at primes dividing $2qr$ and analyze the contribution of trivial solutions. We identify a general obstruction to the modular method that accounts for its failure in many instances. As an application, assuming a standard large image conjecture, we prove that the previous equation admits no nontrivial primitive solutions $(a,b,c)$ with $3 \nmid c$, when $q=5,$ $r=3$ and $p$ is a prime sufficiently large.