In this paper, we consider the exponential Diophantine equation ax+by=cz, where a,b,c be relatively prime positive integers such that a2+b2=cr,r∈Z+,2∣r with b even. That is a=∣Re(m+n−1)r∣,b=∣Im(m+n−1)r∣,c=m2+n2, where m,n are positive integers with m>n,m−n≡1(mod2), gcd(m,n)=1.(x,y,z)=(2,2,r) is called the trivial solution of the equation. In this paper we prove that the equation has no nontrivial solutions in positive integers x,y,z when r≡2(mod4),m≡3(mod4),m>max{n10.4×1011log(5.2×1011logn),3er,70.2nr}. Especially the equation has no nontrivial solutions in positive integers x,y,z when r=2,m≡3(mod4),m>n10.4×1011log(5.2×1011logn).