English

Objective and efficient inference for couplings in neuronal networks

Neurons and Cognition 2020-01-29 v1 Disordered Systems and Neural Networks Statistical Mechanics Adaptation and Self-Organizing Systems

Abstract

Inferring directional couplings from the spike data of networks is desired in various scientific fields such as neuroscience. Here, we apply a recently proposed objective procedure to the spike data obtained from the Hodgkin--Huxley type models and in vitro neuronal networks cultured in a circular structure. As a result, we succeed in reconstructing synaptic connections accurately from the evoked activity as well as the spontaneous one. To obtain the results, we invent an analytic formula approximately implementing a method of screening relevant couplings. This significantly reduces the computational cost of the screening method employed in the proposed objective procedure, making it possible to treat large-size systems as in this study.

Keywords

Cite

@article{arxiv.1805.07061,
  title  = {Objective and efficient inference for couplings in neuronal networks},
  author = {Yu Terada and Tomoyuki Obuchi and Takuya Isomura and Yoshiyuki Kabashima},
  journal= {arXiv preprint arXiv:1805.07061},
  year   = {2020}
}
R2 v1 2026-06-23T01:59:34.166Z