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NORI: Fast probabilistic inference for ambiguous observation-entity mappings

Quantitative Methods 2026-05-13 v1

Abstract

NORI performs probabilistic inference to resolve ambiguous mappings between experimental observations and biological entities orders of magnitude faster than state-of-the-art methods. This makes large-scale analysis and extensive hyperparameter optimization possible, and supports a broader range of bioinformatics applications, including protein inference, taxonomic and functional analysis in omics-fields.

Cite

@article{arxiv.2605.11648,
  title  = {NORI: Fast probabilistic inference for ambiguous observation-entity mappings},
  author = {Simon Van de Vyver and Tibo Vande Moortele and Ben-Björn Binke and Pieter Verschaffelt and Peter Dawyndt and Bart Mesuere},
  journal= {arXiv preprint arXiv:2605.11648},
  year   = {2026}
}

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8 pages, 1 table