We investigate the quantum nonlocality via the discrimination on two, three and four-qubit orthogonal product bases (OPBs). We show that every two-qubit, and some three and four-qubit OPBs can be locally distinguished. It turns out that the remaining three and four-qubit OPBs cannot be locally distinguished, and thus they show the quantum nonlocality without entanglement. We also distinguish them by merging some systems using quantum teleportation with assisted Bell states.