English

Noise-assisted spike propagation in myelinated neurons

Neurons and Cognition 2009-11-13 v1

Abstract

We consider noise-assisted spike propagation in myelinated axons within a multi-compartment stochastic Hodgkin-Huxley model. The noise originates from a finite number of ion channels in each node of Ranvier. For the subthreshold internodal electric coupling, we show that (i) intrinsic noise removes the sharply defined threshold for spike propagation from node to node, and (ii) there exists an optimum number of ion channels which allows for the most efficient signal propagation and it corresponds to the actual physiological values.

Keywords

Cite

@article{arxiv.0811.3371,
  title  = {Noise-assisted spike propagation in myelinated neurons},
  author = {Anna Ochab-Marcinek and Gerhard Schmid and Igor Goychuk and Peter Hänggi},
  journal= {arXiv preprint arXiv:0811.3371},
  year   = {2009}
}

Comments

8 pages, 12 figures, accepted for publication in Phys. Rev. E

R2 v1 2026-06-21T11:43:44.146Z