With the sponsorship of ``Fundacio La Caixa'' we met in Barcelona, November 21st and 22nd, to analyze the reasons why, after the completion of the human genome sequence, the identification all protein coding genes and their variants remains a distant goal. Here we report on our discussions and summarize some of the major challenges that need to be overcome in order to complete the human gene catalog.
@article{arxiv.q-bio/0410008,
title = {Needed for completion of the human genome: hypothesis driven experiments and biologically realistic mathematical models},
author = {Roderic Guigo and Ewan Birney and Michael Brent and Emmanouil Dermitzakis and Lior Pachter and Hugues Roest Crollius and Victor Solovyev and Michael Q. Zhang},
journal= {arXiv preprint arXiv:q-bio/0410008},
year = {2007}
}
Comments
Report and discussion resulting from the `Fundacio La Caixa' gene finding meeting held November 21 and 22 2003 in Barcelona