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Multiscale Computation of a Polypeptide Backbone Model

Materials Science 2007-05-23 v1 Statistical Mechanics

Abstract

The multiscale Monte-Carlo algorithm outlined in Bai and Brandt[1] is applied to a simple model of the polypeptide backbone. Effective coarse level Hamiltonians are derived by a fast Newtonian iterative scheme. The coarse Hamiltonian parameters are adjusted so that local structural properties have the same value in both coarse and fine level simulations. It is demonstrated that at convergence of iterations, global structural properties are reproduced very well in coarse level simulations.

Keywords

Cite

@article{arxiv.cond-mat/0312185,
  title  = {Multiscale Computation of a Polypeptide Backbone Model},
  author = {Dov Bai},
  journal= {arXiv preprint arXiv:cond-mat/0312185},
  year   = {2007}
}

Comments

Submitted to Journal of Computational Chemistry