English

Multiple conditional randomization tests for lagged and spillover treatment effects

Statistics Theory 2024-10-14 v6 Methodology Statistics Theory

Abstract

We consider the problem of constructing multiple independent conditional randomization tests using a single dataset. Because the tests are independent, the randomization p-values can be interpreted individually and combined using standard methods for multiple testing. We give a simple, sequential construction of such tests, and then discuss its application to three problems: Rosenbaum's evidence factors for observational studies, lagged treatment effect in stepped-wedge trials, and spillover effect in randomized trials with interference. We compare the proposed approach with some existing methods using simulated and real datasets. Finally, we establish a more general sufficient condition for independent conditional randomization tests.

Keywords

Cite

@article{arxiv.2104.10618,
  title  = {Multiple conditional randomization tests for lagged and spillover treatment effects},
  author = {Yao Zhang and Qingyuan Zhao},
  journal= {arXiv preprint arXiv:2104.10618},
  year   = {2024}
}

Comments

43 pages, 7 figures; Part of the original version of this paper can be found at arXiv:2203.10980; To appear in Biometrika

R2 v1 2026-06-24T01:24:18.027Z