English

Multi-Task Time Series Analysis applied to Drug Response Modelling

Machine Learning 2019-03-22 v1 Machine Learning

Abstract

Time series models such as dynamical systems are frequently fitted to a cohort of data, ignoring variation between individual entities such as patients. In this paper we show how these models can be personalised to an individual level while retaining statistical power, via use of multi-task learning (MTL). To our knowledge this is a novel development of MTL which applies to time series both with and without control inputs. The modelling framework is demonstrated on a physiological drug response problem which results in improved predictive accuracy and uncertainty estimation over existing state-of-the-art models.

Keywords

Cite

@article{arxiv.1903.08970,
  title  = {Multi-Task Time Series Analysis applied to Drug Response Modelling},
  author = {Alex Bird and Christopher K. I. Williams and Christopher Hawthorne},
  journal= {arXiv preprint arXiv:1903.08970},
  year   = {2019}
}

Comments

To appear in AISTATS 2019

R2 v1 2026-06-23T08:14:57.541Z