English

Modeling Drug-Disease Relations with Linguistic and Knowledge Graph Constraints

Computation and Language 2019-04-02 v1

Abstract

FDA drug labels are rich sources of information about drugs and drug-disease relations, but their complexity makes them challenging texts to analyze in isolation. To overcome this, we situate these labels in two health knowledge graphs: one built from precise structured information about drugs and diseases, and another built entirely from a database of clinical narrative texts using simple heuristic methods. We show that Probabilistic Soft Logic models defined over these graphs are superior to text-only and relation-only variants, and that the clinical narratives graph delivers exceptional results with little manual effort. Finally, we release a new dataset of drug labels with annotations for five distinct drug-disease relations.

Keywords

Cite

@article{arxiv.1904.00313,
  title  = {Modeling Drug-Disease Relations with Linguistic and Knowledge Graph Constraints},
  author = {Bruno Godefroy and Christopher Potts},
  journal= {arXiv preprint arXiv:1904.00313},
  year   = {2019}
}
R2 v1 2026-06-23T08:24:13.552Z