Modeling and Analysis of Abnormality Detection in Biomolecular Nano-Networks
Abstract
A scheme for detection of abnormality in molecular nano-networks is proposed. This is motivated by the fact that early diagnosis, classification and detection of diseases such as cancer play a crucial role in their successful treatment. The proposed nano-abnormality detection scheme (NADS) comprises of a two-tier network of sensor nano-machines (SNMs) in the first tier and a data gathering node (DGN) at the sink. The SNMs detect the presence of competitor cells as abnormality that is captured by variations in parameters of a nano-communications channel. In the second step, the SNMs transmit micro-scale messages over a noisy micro communications channel (MCC) to the DGN, where a decision is made upon fusing the received signals. The detection performance of each SNM is analyzed by setting up a Neyman-Pearson test. Next, taking into account the effect of the MCC, the overall performance of the proposed NADS is quantified in terms of probabilities of misdetection and false alarm. A design problem is formulated, when the optimized concentration of SNMs in a sample is obtained for a high probability of detection and a limited probability of false alarm.
Keywords
Cite
@article{arxiv.1205.6752,
title = {Modeling and Analysis of Abnormality Detection in Biomolecular Nano-Networks},
author = {Siavash Ghavami and Farshad Lahouti and Ali Masoudi-Nejad},
journal= {arXiv preprint arXiv:1205.6752},
year = {2016}
}
Comments
31 pages, 13 figures, Invited from IEEE MoNaCom 2012 to Journal of Nano Communication Networks