English

Isotonized smooth estimators of a monotone baseline hazard in the Cox model

Statistics Theory 2018-05-18 v2 Statistics Theory

Abstract

We consider two isotonic smooth estimators for a monotone baseline hazard in the Cox model, a maximum smooth likelihood estimator and a Grenander-type estimator based on the smoothed Breslow estimator for the cumulative baseline hazard. We show that they are both asymptotically normal at rate nm/(2m+1)n^{m/(2m+1)}, where m2m\geq 2 denotes the level of smoothness considered, and we relate their limit behavior to kernel smoothed isotonic estimators studied in Lopuha\"a and Musta (2016). It turns out that the Grenander-type estimator is asymptotically equivalent to the kernel smoothed isotonic estimators, while the maximum smoothed likelihood estimator exhibits the same asymptotic variance but a different bias. Finally, we present numerical results on pointwise confidence intervals that illustrate the comparable behavior of the two methods.

Keywords

Cite

@article{arxiv.1611.01506,
  title  = {Isotonized smooth estimators of a monotone baseline hazard in the Cox model},
  author = {Hendrik P. Lopuhaä and Eni Musta},
  journal= {arXiv preprint arXiv:1611.01506},
  year   = {2018}
}

Comments

arXiv admin note: text overlap with arXiv:1609.06617