Isoform reconstruction using short RNA-Seq reads by maximum likelihood is NP-hard
Quantitative Methods
2013-05-07 v1 Genomics
Abstract
Maximum likelihood is a popular technique for isoform reconstruction. Here, we show that isoform reconstruction using short RNA-Seq reads by maximum likelihood is NP-hard.
Cite
@article{arxiv.1305.0916,
title = {Isoform reconstruction using short RNA-Seq reads by maximum likelihood is NP-hard},
author = {Tianyang Li and Rui Jiang and Xuegong Zhang},
journal= {arXiv preprint arXiv:1305.0916},
year = {2013}
}
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