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Is Heteropolymer Freezing Well Described by the Random Energy Model?

Condensed Matter 2009-10-28 v1 q-bio

Abstract

It is widely held that the Random Energy Model (REM) describes the freezing transition of a variety of types of heteropolymers. We demonstrate that the hallmark property of REM, statistical independence of the energies of states over disorder, is violated in different ways for models commonly employed in heteropolymer freezing studies. The implications for proteins are also discussed.

Keywords

Cite

@article{arxiv.cond-mat/9604147,
  title  = {Is Heteropolymer Freezing Well Described by the Random Energy Model?},
  author = {Vijay S. Pande and Alexander Yu. Grosberg and Chris Joerg and Toyoichi Tanaka},
  journal= {arXiv preprint arXiv:cond-mat/9604147},
  year   = {2009}
}

Comments

4 pages, 3 eps figures To appear in Physical Review Letters, May 1996