Investigating the thermodynamics of small biosystems with optical tweezers
Mesoscale and Nanoscale Physics
2010-01-18 v1 Statistical Mechanics
Biological Physics
Biomolecules
Abstract
We present two examples of how single-molecule experimental techniques applied to biological systems can give insight into problems within the scope of equilibrium and nonequilibrium mesoscopic thermodynamics. The first example is the mapping of the free energy landscape of a macromolecule, the second the experimental verification of Crooks' fluctuation theorem. In both cases the experimental setup comprises optical tweezers and DNA molecules.
Keywords
Cite
@article{arxiv.0904.3197,
title = {Investigating the thermodynamics of small biosystems with optical tweezers},
author = {Alessandro Mossa and Josep Maria Huguet and Felix Ritort},
journal= {arXiv preprint arXiv:0904.3197},
year = {2010}
}
Comments
6 pages, 9 figures, Proceedings of the conference Frontiers of Quantum and Mesoscopic Thermodynamics, Prague 2008