English

Interpretable meta-analysis of model or marker performance

Methodology 2024-09-23 v1

Abstract

Conventional meta analysis of model performance conducted using datasources from different underlying populations often result in estimates that cannot be interpreted in the context of a well defined target population. In this manuscript we develop methods for meta-analysis of several measures of model performance that are interpretable in the context of a well defined target population when the populations underlying the datasources used in the meta analysis are heterogeneous. This includes developing identifiablity conditions, inverse-weighting, outcome model, and doubly robust estimator. We illustrate the methods using simulations and data from two large lung cancer screening trials.

Keywords

Cite

@article{arxiv.2409.13458,
  title  = {Interpretable meta-analysis of model or marker performance},
  author = {Jon A. Steingrimsson and Lan Wen and Sarah Voter and Issa J. Dahabreh},
  journal= {arXiv preprint arXiv:2409.13458},
  year   = {2024}
}
R2 v1 2026-06-28T18:51:20.134Z