Fluctuations in the spontaneous beating activity of isolated cardiac cells were studied over a timescale of six decades. The beat dynamics of single cardiac cells were heterogeneous and intermittent. The interbeat intervals (IBIs) were power-law distributed in a long-time regime. Furthermore, for long timescales up to the experimental window, the autocorrelation of IBIs exhibits a scaling behavior of 1/f^beta-noise type. These observations suggest that 1/f^beta noise is an intrinsic characteristic of spontaneous activity of single cardiac cells.
@article{arxiv.0708.2308,
title = {Intermittent dynamics and 1/f^beta noise in single cardiac muscle cells},
author = {Tomomi Yokogawa and Takahiro Harada},
journal= {arXiv preprint arXiv:0708.2308},
year = {2007}
}