The Benalcazar-Bernevig-Hughes(BBH) model is one of the most representative higher-order topological insulators with different bulk-edge correspondence comparing conventional topological states. In this work, we propose to realize a couple-BBH model with glide reflection symmetry by coupling two topologically distinct BBH models. Such a system gives rise to intriguing properties beyond the traditional BBH model. A topological phase transition from higher-order topological phase to a semimetal has been predicted in this system. Furthermore, the band crossing points and nodal ring protected by glide reflection symmetry has also been explored. Our work provides a viewpoint to demonstrate the versatile phenomena induced by the interplay between higher-order topology and nonsymmorphic symmetries.