English

Geometry-Dependent Defect Merging Induces Bifurcated Dynamics in Active Networks

Soft Condensed Matter 2025-09-10 v3 Biological Physics

Abstract

Cytoskeletal networks can repair defects to maintain structural integrity. However, the mechanisms and dynamics of defect merging remain poorly understood. Here we report a geometry-tunable merging mechanism in microtubule-motor networks initiated by active crosslinking. We directly generate defects using a light-controlled microtubule-motor system in O-shaped and V-shaped networks, and observe that the defects can self-close. Combining theory and experiment, we find that the V-shaped networks must overcome internal elastic resistance in order to zip up cracks, giving rise to a bifurcation of dynamics dependent on the initial opening angle of the crack: the crack merges below a critical angle and opens up at larger angles. Simulation of a continuum model reproduces the bifurcation dynamics, revealing the importance of overlapping boundary layers where free motors and microtubules can actively crosslink and thereby merge the defects. We also formulate a simple elastic-rod model that can qualitatively predict the critical angle, which is tunable by the network geometry.

Keywords

Cite

@article{arxiv.2407.00842,
  title  = {Geometry-Dependent Defect Merging Induces Bifurcated Dynamics in Active Networks},
  author = {Fan Yang and Shichen Liu and Hao Wang and Heun Jin Lee and Rob Phillips and Matt Thomson},
  journal= {arXiv preprint arXiv:2407.00842},
  year   = {2025}
}
R2 v1 2026-06-28T17:24:15.520Z