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From Foundation ECG Models to NISQ Learners: Distilling ECGFounder into a VQC Student

Quantum Physics 2026-03-31 v1 Artificial Intelligence

Abstract

Foundation models have recently improved electrocardiogram (ECG) representation learning, but their deployment can be limited by computational cost and latency constraints. In this work, we fine-tune ECGFounder as a high-capacity teacher for binary ECG classification on PTB-XL and the MIT-BIH Arrhythmia Database, and investigate whether knowledge distillation can transfer its predictive behavior to compact students. We evaluate two classical 1D students (ResNet-1D and a lightweight CNN-1D) and a quantum-ready pipeline that combines a convolutional autoencoder, which compresses 256-sample ECG windows into a low-dimensional latent representation, with a 6-qubit variational quantum circuit implemented in Qiskit and executed in a simulated backend. Across both datasets, the teacher provides the strongest overall performance, while distillation yields competitive students under a considerable reduction in trainable parameters. We further analyze the sensitivity of student performance to distillation settings, highlighting consistent accuracy--efficiency trade-offs when compressing a foundation ECG model into classical and quantum-ready learners under a unified evaluation protocol.

Keywords

Cite

@article{arxiv.2603.27269,
  title  = {From Foundation ECG Models to NISQ Learners: Distilling ECGFounder into a VQC Student},
  author = {Giovanni dos Santos Franco and Felipe Mahlow and Ellison Fernando Cardoso and Felipe Fanchini},
  journal= {arXiv preprint arXiv:2603.27269},
  year   = {2026}
}