Fodis: software for protein unfolding analysis
Biomolecules
2018-09-28 v2
Abstract
The folding dynamics of proteins at the single molecule level has been studied with single-molecule force spectroscopy (SMFS) experiments for twenty years, but a common standardized method for the analysis of the collected data and for the sharing among the scientific community members is still not available. We have developed a new open source tool, Fodis, for the analysis of the Force-distance curves obtained in SMFS experiments, providing an almost automatic processing, analysis and classification of the obtained data. Our method provides also a classification of the possible unfolding pathways and structural heterogeneity, present during the unfolding of proteins.
Cite
@article{arxiv.1803.11386,
title = {Fodis: software for protein unfolding analysis},
author = {Nicola Galvanetto and Andrea Perissinotto and Andrea Pedroni and Vincent Torre},
journal= {arXiv preprint arXiv:1803.11386},
year = {2018}
}