This study details the use of printing and other additive processes to fabricate a novel amperometric glucose sensor. The sensor was fabricated using a Au coated 12.7 micron polyimide film as a starting material, where micro-contact printing, electrochemical plating and chloridization, electrohydrodynamic jet (e-jet) printing, and spin coating were used to pattern, deposit, print, and coat functional materials, respectively. We have found that e-jet printing was effective for the deposition and patterning of glucose oxidase inks between ~5 to 1000 micron in width, and we have demonstrated that the enzyme was still active after printing. The thickness of the permselective layer was optimized to obtain a linear response to glucose concentration up to 32 mM. For these sensors no response to acetaminophen, a common interfering compound, was observed.
@article{arxiv.1411.6167,
title = {Fabrication and Characterization of an Amperometric Glucose Sensor on a Flexible Polyimide Substrate},
author = {Xiaosong Du and Christopher J. Durgan and David J. Matthews and Joshua R. Motley and Xuebin Tan and Kovit Pholsena and Líney Árnadóttir and Jessica R. Castle and Peter G. Jacobs and Robert S. Cargill and W. Kenneth Ward and John F. Conley and Gregory S. Herman},
journal= {arXiv preprint arXiv:1411.6167},
year = {2015}
}
Comments
This paper has been withdrawn by the author due to a crucial error in Figure 4 and 6