Enzyme-enriched condensates show self-propulsion, positioning, and coexistence
Biological Physics
2023-03-29 v1 Soft Condensed Matter
Abstract
Enzyme-enriched condensates can organize the spatial distribution of their substrates by catalyzing non-equilibrium reactions. Conversely, an inhomogeneous substrate distribution induces enzyme fluxes through substrate-enzyme interactions. We find that condensates move towards the center of a confining domain when this feedback is weak. Above a feedback threshold, they exhibit self-propulsion, leading to oscillatory dynamics. Moreover, catalysis-driven enzyme fluxes can lead to interrupted coarsening, resulting in equidistant condensate positioning, and to condensate division.
Keywords
Cite
@article{arxiv.2301.00392,
title = {Enzyme-enriched condensates show self-propulsion, positioning, and coexistence},
author = {Leonardo Demarchi and Andriy Goychuk and Ivan Maryshev and Erwin Frey},
journal= {arXiv preprint arXiv:2301.00392},
year = {2023}
}