Entropy facilitated active transport
Biomolecules
2017-05-24 v1 Soft Condensed Matter
Biological Physics
Abstract
We show how active transport of ions can be interpreted as an entropy facilitated process. In this interpretation, the pore geometry through which substrates are transported can give rise to a driving force. This gives a direct link between the geometry and the changes in Gibbs energy required. Quantifying the size of this effect for several proteins we find that the entropic contribution from the pore geometry is significant and we discuss how the effect can be used to interpret variations in the affinity at the binding site.
Cite
@article{arxiv.1701.02943,
title = {Entropy facilitated active transport},
author = {J. M. Rubi and A. Lervik and D. Bedeaux and S. Kjelstrup},
journal= {arXiv preprint arXiv:1701.02943},
year = {2017}
}
Comments
9 pages, 3 figures