Electromigration dispersion in Capillary Electrophoresis
Biological Physics
2012-03-07 v1 Soft Condensed Matter
Quantitative Methods
Abstract
In a previous paper (S. Ghosal and Z. Chen Bull. Math. Biol. 2010, vol. 72, pg. 2047) it was shown that the evolution of the solute concentration in capillary electrophoresis is described by a nonlinear wave equation that reduced to Burger's equation if the nonlinearity was weak. It was assumed that only strong electrolytes (fully dissociated) were present. In the present paper it is shown that the same governing equation also describes the situation where the electrolytic buffer consists of a single weak acid (or base). A simple approximate formula is derived for the dimensionless peak variance which is shown to agree well with published experimental data.
Keywords
Cite
@article{arxiv.1203.1062,
title = {Electromigration dispersion in Capillary Electrophoresis},
author = {Zhen Chen and Sandip Ghosal},
journal= {arXiv preprint arXiv:1203.1062},
year = {2012}
}
Comments
10 pages, 2 figures