Dissortativity and duplications in Oral cancer
Molecular Networks
2016-03-08 v1
Abstract
More than 300,000 new cases worldwide are being diagnosed with oral cancer annually. Complexity of oral cancer renders designing drug targets very difficult. We analyse protein-protein interaction network for the normal and oral cancer tissue and detect crucial changes in the structural properties of the networks in terms of the interactions of the hub proteins and the degree-degree correlations. Further analysis of the spectra of both the networks, while exhibiting universal statistical behavior, manifest distinction in terms of the zero degeneracy, providing insight to the complexity of the underlying system.
Keywords
Cite
@article{arxiv.1602.07170,
title = {Dissortativity and duplications in Oral cancer},
author = {Pramod Shinde and Alok Yadav and Aparna Rai and Sarika Jalan},
journal= {arXiv preprint arXiv:1602.07170},
year = {2016}
}