English

Discrete Nonlinear Schrodinger Equation, Solitons and Organizing Principles for Protein Folding

Biological Physics 2021-02-24 v1 Soft Condensed Matter Mathematical Physics math.MP

Abstract

We introduce a novel generalization of the discrete nonlinear Schr\"odinger equation. It supports solitons that describe how proteins fold. As an example we scrutinize the villin headpiece HP35, an archetypal protein for testing both experimental and theoretical approaches to protein folding. Using explicit soliton profiles we construct its carbon backbone with an unprecedented accuracy.

Keywords

Cite

@article{arxiv.1009.1078,
  title  = {Discrete Nonlinear Schrodinger Equation, Solitons and Organizing Principles for Protein Folding},
  author = {Nora Molkenthin and Shuangwei Hu and Antti J. Niemi},
  journal= {arXiv preprint arXiv:1009.1078},
  year   = {2021}
}

Comments

5 pages 2 figures