Destruction of CD4 T Lymphocytes Alone Cannot Account for their Long-term Decrease in AIDS
Dynamical Systems
2025-10-20 v1 Numerical Analysis
Mathematical Physics
math.MP
Numerical Analysis
q-bio
Abstract
Following previous models describing a quasi steady state (QSS) for the evolution of HIV infection and AIDS, we have developed a larger formalism simulating the long-term evolution of the QSS We show that the long-term evolution of AIDS cannot be explained by the destruction alone of CD4 T cells, either directly or indirectly. The destruction of CD4 T cells can lead only to a QSS with a lower concentration of CD4 T cells, but CD4 destruction cannot generate the sustained long-term decrease in T cells leading to AIDS. We here suggest some workable explanations.
Cite
@article{arxiv.math/0008052,
title = {Destruction of CD4 T Lymphocytes Alone Cannot Account for their Long-term Decrease in AIDS},
author = {Yoram Louzoun and Irun. R. Cohen and Henri Atlan},
journal= {arXiv preprint arXiv:math/0008052},
year = {2025}
}
Comments
5 pages 4 figures