Desensitization of a balance with Langmuir binding of weights
Biological Physics
2007-05-23 v1 Quantitative Methods
Abstract
A balance is described with Langmuir binding of weights to each side. This simple physical system, when coupled with a previously derived equation for the equivalent displacement of weight that perturbs the equilibrium of a balance, models two-state, receptor systems in pharmacology for receptor activation. Surprisingly, this system also shows desensitization similar to many drug-receptor systems. Although understanding the biophysics behind receptor signaling is an important endeavor by itself, this analogy with a simple balance may bring new insights into other areas of physics as well.
Keywords
Cite
@article{arxiv.physics/0303055,
title = {Desensitization of a balance with Langmuir binding of weights},
author = {Richard Lanzara},
journal= {arXiv preprint arXiv:physics/0303055},
year = {2007}
}
Comments
11 pages with 3 embedded figures