English

Delineation of the Native Basin in Continuum Models of Proteins

Soft Condensed Matter 2009-10-31 v1 Statistical Mechanics q-bio

Abstract

We propose two approaches for determining the native basins in off-lattice models of proteins. The first of them is based on exploring the saddle points on selected trajectories emerging from the native state. In the second approach, the basin size can be determined by monitoring random distortions in the shape of the protein around the native state. Both techniques yield the similar results. As a byproduct, a simple method to determine the folding temperature is obtained.

Keywords

Cite

@article{arxiv.cond-mat/9908171,
  title  = {Delineation of the Native Basin in Continuum Models of Proteins},
  author = {Mai Suan Li and Marek Cieplak},
  journal= {arXiv preprint arXiv:cond-mat/9908171},
  year   = {2009}
}

Comments

REVTeX, 6 pages, 5 EPS figures